Neural Tube Defects – Role of Folate , Prevention Strategies

نویسنده

  • Nejat Akar
چکیده

Neural tube defects (NTD) are severe congenital malformations and can be fatal. These malformations constitute one of the principal causes of mortality and morbidity in childhood. Classically, NTD have been divided into two main groups: (a) defects affecting cranial structures, such as anencephaly and encephalocele, and (b) defects involving spinal structures (spina bifida) (Verrotti et al., 2006). In newer classification schemes for the NTD, encephalocele shows more similarities to spina bifida or anencephaly than it shows differences with respect to characteristics, temporal trend and the impact of fortification (Rowland et al., 2006).

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تاریخ انتشار 2012